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	Provedor de dados Biol. Res. (5) BJMBR (2) International Journal of Morphology (1) Autor ITURRIAGA,RODRIGO (2) Clarke,J.A. (1) DEL RÍO,RODRIGO (1) Daly,M. de B. (1) Del Rio,Rodrigo (1) Dolhnikoff,M. (1) EYZAGUIRRE,CARLOS (1) Ead,H.W. (1) Hassanali,Jameela (1) Hennessy,E.M. (1) Idiaquez,Juan (1) Iturriaga,Rodrigo (1) LARRAÍN,CAROLINA (1) Malek,Adel A (1) Mandela,Pamella (1) Muthoka,Johnstone M (1) Ogeng'o,Julius A (1) REY,SERGIO (1) Saldiva,P.H.N. (1) Somers,Virend K. (1) Mais... Palavra-chave Carotid body (8) Chemosensory activity (3) Hypoxia (2) Obstructive sleep apnea (2) Acute respiratory distress syndrome (1) Arterial chemoreceptors (1) Autonomic dysfunction (1) Chemoreceptor (1) Co-cultures (1) Cultures (1) Cytochrome oxidase (1) Diabetic rat (1) Glomus cells (1) Heart failure (1) In situ (1) In vitro (1) Intermittent hypoxia (1) Kenyan (1) Metabolic syndrome (1) Morphometry (1) Mais... Tipo do documento Journal article (6) Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2016 (1) 2011 (1) 2005 (3) 2002 (1) 2001 (1) 1999 (1) Mais... País Chile (6) Brazil (2) Idioma Inglês (8)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 8 Primeira ... 1 ... Última Cardiovascular and ventilatory acclimatization induced by chronic intermittent hypoxia: A role for the carotid body in the pathophysiology of sleep apnea Biol. Res. ITURRIAGA,RODRIGO; REY,SERGIO; DEL RÍO,RODRIGO. Patients with obstructive sleep apnea (OSA) show augmented ventilatory, sympathetic and cardiovascular responses to hypoxia. The facilitatory effect of chronic intermittent hypoxia (CIH) on the hypoxic ventilatory response has been attributed to a potentiation of the carotid body (CB) chemosensory response to hypoxia. However, it is a matter of debate whether the effects induced by CIH on ventilatory responses to hypoxia are due to an enhanced CB activity. Recently, we studied the effects of short cyclic hypoxic episodes on cat cardiorespiratory reflexes, heart rate variability, and CB chemosensory activity. Cats were exposed to cyclic hypoxic episodes repeated during 8 hours for 4 days. Our results showed that CIH selectively enhanced ventilatory and... Tipo: Journal article Palavras-chave: Ventilatory acclimatization; Carotid body; Chemosensory activity; Intermittent hypoxia; Obstructive sleep apnea. Ano: 2005 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000400004 Carotid body (Thermoreceptors, sympathetic neural activation, and cardiometabolic disease Biol. Res. Iturriaga,Rodrigo; Del Rio,Rodrigo; Idiaquez,Juan; Somers,Virend K.. The carotid body (CB) is the main peripheral chemoreceptor that senses the arterial PO2, PCO2 and pH. In response to hypoxemia, hypercapnia and acidosis, carotid chemosensory discharge elicits reflex respiratory, autonomic and cardiovascular adjustments. The classical construct considers the CB as the main peripheral oxygen sensor, triggering reflex physiological responses to acute hypoxemia and facilitating the ventilatory acclimation to chronic hypoxemia at high altitude. However, a growing body of experimental evidence supports the novel concept that an abnormally enhanced CB chemosensory input to the brainstem contributes to overactivation of the sympathetic nervous system, and consequent pathology. Indeed, the CB has been implicated in several... Tipo: Journal article Palavras-chave: Autonomic dysfunction; Carotid body; Heart failure; Metabolic syndrome; Obstructive sleep apnea; Sympathetic activation. Ano: 2016 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602016000100013 Chemical and electric transmission in the carotid body chemoreceptor complex Biol. Res. EYZAGUIRRE,CARLOS. Carotid body chemoreceptors are complex secondary receptors. There are chemical and electric connections between glomus cells (GC/GC) and between glomus cells and carotid nerve endings (GC/NE). Chemical secretion of glomus cells is accompanied by GC/GC uncoupling. Chemical GC/NE transmission is facilitated by concomitant electric coupling. Chronic hypoxia reduces GC/GC coupling but increases G/NE coupling. Therefore, carotid body chemoreceptors use chemical and electric transmission mechanisms to trigger and change the sensory discharge in the carotid nerve. Tipo: Journal article Palavras-chave: Carotid body; Chemosensory activity; Glomus cells. Ano: 2005 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000400005 How the carotid body works: Different strategies and preparations to solve different problems Biol. Res. ZAPATA,PATRICIO; LARRAÍN,CAROLINA. This is a review of the different experimental approaches developed to solve the problems in our progress towards a comprehensive understanding of how arterial chemoreceptors operate. An analysis is performed of the bases, advantages and limits of the following preparations: studies of ventilatory reflexes originated from carotid bodies (CBs) in the entire animal; recordings of CB chemosensory discharges in situ; CB preparations perfused in situ; CB explants in oculo; CB explants in ovo; CB preparations incubated in vitro; CB preparations superfused in vitro; CB preparations perfused and superfused in vitro; CB tissue slices in vitro; cells acutely dissociated from CBs; CB cells in tissue culture; petrosal ganglia superfused in vitro; petrosal ganglion... Tipo: Journal article Palavras-chave: Arterial chemoreceptors; Carotid body; Chemosensory activity; Co-cultures; Cultures; In situ; In vitro; Petrosal ganglia; Superfusion. Ano: 2005 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000400002 Morphological changes of carotid bodies in acute respiratory distress syndrome: a morphometric study in humans BJMBR Vinhaes,E.N.G.; Dolhnikoff,M.; Saldiva,P.H.N.. Carotid bodies are chemoreceptors sensitive to a fall of partial oxygen pressure in blood (hypoxia). The morphological alterations of these organs in patients with chronic obstructive pulmonary disease (COPD) and in people living at high altitude are well known. However, it is not known whether the histological profile of human carotid bodies is changed in acute clinical conditions such as acute respiratory distress syndrome (ARDS). The objective of the present study was to perform a quantitative analysis of the histology of carotid bodies collected from patients who died of ARDS. A morphometric study of carotid bodies collected during routine autopsies was carried out on three groups: patients that died of non-respiratory diseases (controls, N = 8),... Tipo: Info:eu-repo/semantics/article Palavras-chave: Carotid body; Hypoxia; Acute respiratory distress syndrome; Morphometry. Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002001000002 Nitric oxide and carotid body chemoreception Biol. Res. ITURRIAGA,RODRIGO. Nitric oxide (NO) has been proposed as an inhibitory modulator of carotid body chemosensory responses to hypoxia. It is believed that NO modulates carotid chemoreception by several mechanisms, which include the control of carotid body vascular tone and oxygen delivery and reduction of the excitability of chemoreceptor cells and petrosal sensory neurons. In addition to the well-known inhibitory effect, we found that NO has a dual (dose-dependent) effect on carotid chemoreception depending on the oxygen pressure level. During hypoxia, NO is primarily an inhibitory modulator of carotid chemoreception, while in normoxia NO increased the chemosensory activity. This excitatory effect produced by NO is likely mediated by an impairment of mitochondrial electron... Tipo: Journal article Palavras-chave: Carotid body; Chemoreceptor; Cytochrome oxidase; Hypoxia; Nitric oxide; Oxidative phosphorylation. Ano: 2001 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602001000200019 Position and Blood Supply of the Carotid Body in a Kenyan Population International Journal of Morphology Muthoka,Johnstone M; Hassanali,Jameela; Mandela,Pamella; Ogeng'o,Julius A; Malek,Adel A. Position and source of blood supply to the human carotid body displays population variations. These data are important during surgical procedures and diagnostic imaging in the neck but are only scarcely reported and altogether missing for the Kenyan population. The aim of this study was to describe the position and blood supply of the carotid body in a Kenyan population. A descriptive cross-sectional study at the Department of Human Anatomy, University of Nairobi, was designed. 136 common carotid arteries and their bifurcations were exposed by gross dissection. The carotid body was identified as a small oval structure embedded in the blood vessel adventitia. Position and source of blood supply were photographed. Data are presented by tables and... Tipo: Journal article Palavras-chave: Carotid body; Position; Variations; Kenyan. Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000100010 The carotid body of the spontaneous insulin-dependent diabetic rat BJMBR Clarke,J.A.; Daly,M. de B.; Ead,H.W.; Hennessy,E.M.. The carotid bodies from adult spontaneous insulin-dependent diabetic rats (strain BB/S) were perfusion-fixed at normal arterial blood pressure with 3% phosphate-buffered glutaraldehyde and compared with the organs from control rats (strain BB/Sc) prepared in the same way. Serial 5-µm sections were cut, stained, and using an interactive image analysis system, were analysed to determine the volumes of the carotid body and its vascular and extravascular compartments. There was no evidence of systemic arterial disease in the carotid stem arteries in either group of animals, and the microvasculature of the organs appeared normal by light microscopy. The volume of the carotid body was unchanged 3 months after the onset of diabetes but was increased at 6 months.... Tipo: Info:eu-repo/semantics/other Palavras-chave: Diabetic rat; Carotid body; Quantitative morphology; Vascular compartment. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000100013 Registros recuperados: 8 Primeira ... 1 ... Última

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